GenOne is a gentamicin sulfate with betamethasone valerate topical spray that is indicated for the treatment in dogs of infected superficial lesions for bacteria sensitive to gentamicin. Each milliliter contains gentamicin sulfate equivalent to 0.57 mg gentamicin base, and betamethasone valerate equivalent to 0.284 mg betamethasone. Gentamicin, a broad-spectrum antibiotic, is a highly effective topical treatment for bacterial infections of the skin. Betamethasone valerate, a synthetic glucocorticoid, has been shown to provide anti-inflammatory and antipruritic activity in the topical management of corticosteroid-responsive infected superficial lesions in dogs. For topical use in dogs only.
Directions: Prior to treatment, remove excessive hair and clean the lesion and adja-cent area. Hold bottle upright 3 to 6 inches from the lesion and depress the sprayer head twice. Administer 2 to 4 times daily for 7 days.
Each depression of the sprayer head delivers 0.7 mL of GenOne™ Spray.
Side effects such as SAP and SGPT enzyme elevations, weight loss, anorexia, polydipsia, and polyuria have occurred following parenteral or systemic use of synthetic corticosteroids in dogs. Vomiting and diarrhea (occasionally bloody) have been observed in dogs. Cushing’s syndrome in dogs has been reported in association with prolonged or repeated steroid therapy.