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adequan canine

Adequan Canine is administered by intramuscular injection for the control of signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints. Adequan Canine contains polysulfated glycosaminoglycan (PSGAG). Polysulfated glycosaminoglycan is characterized as a "disease modifying osteoarthritis drug." Adequan Canine contains 100 mg/ml of polysulfated glycosaminoglycan .


How it works: Adequan Canine contains polysulfated glycosaminoglycans, which are used by the body to make cartilage. When injected intramuscularly, it helps promote the formation of healthy cartilage and joint fluid and supports the body's natural joint repair process. 

What is the most important information I should know about Adequan: Adequan is a prescription medication used in dogs and horses to control signs associated with degenerative or traumatic arthritis. Adequan Canine 100mg/ml is available by prescription in a box containing 2 x 5 ml vials. The usual dose in dogs is 2mg per lb given by intramuscular injection only, twice a week for up to 4 weeks. Adequan Equine 500mg/5ml is available by prescription in a box containing 7 x 5ml ampoules. The usual dose in horses is 500mg given by intramuscular injection every 4 days for 28 days. Do not mix this medication with other drugs or chemicals. 

Dosage and Administration: The recommended dose of Adequan® Canine is 2 mg/lb body weight (.02 mL/lb, or 1 mL per 50 lb), by intramuscular injection only, twice weekly for up to 4 weeks (maximum of 8 injections). Do not exceed the recommended dose or therapeutic regimen. Do not mix Adequan® Canine with other drugs or solvents. 

If you miss a dose: Give the missed dose as soon as you remember. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication. 

What happens if I give an overdose: Overdose is extremely rare. Symptoms that may indicate toxicity include joint pain, swelling and lameness. 

What should I avoid while giving Adequan: Do not give this medication to breeding, pregnant or lactating animals. Use with caution in animals with kidney or liver disease, or blood clotting or coagulation disorders. 

What are the possible side effects of Adequan: Few side effects are seen following Intramuscular injection. Stop giving Adequan and seek emergency veterinary medical attention if an allergic reaction (facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma) should occur. Bleeding from the nose, blood in the feces, or dark and tarry stools may indicate a decreased ability of blood to clot. Contact your veterinarian if you notice these symptoms. Other side effects may also occur. Talk to your veterinarian about any side effects that seem unusual or bothersome to the animal. 

Storage Conditions: Store at controlled room temperature up to 25°C (77°F) (See USP).